|
|
4-hydroxy-L-tryptophan + H+ <=> 4-hydroxytryptamine + CO2
|
4.1.1.105
L-tryptophan decarboxylase
|
–
|
| |
KEGG:
R11932
MetaCyc:
RXN-19124
|
|
|
|
ATP + 4-hydroxytryptamine <=> ADP + 4-hydroxytryptamine_4-phosphate + H+
|
2.7.1.222
4-hydroxytryptamine kinase
|
–
|
| |
BRENDA:
BR52258
KEGG:
R11933
MetaCyc:
RXN-19090
|
|
|
|
H+ + L-tryptophan <=> CO2 + tryptamine
|
4.1.1.105
L-tryptophan decarboxylase
4.1.1.28
aromatic-L-amino-acid decarboxylase
4.1.1.53
phenylalanine decarboxylase
|
–
–
–
|
| |
BRENDA:
BR52265
KEGG:
R00685
MetaCyc:
AROMATIC-L-AMINO-ACID-DECARBOXYLASE-RXN
SABIO-RK:
1065
|
|
|
|
S-adenosyl-L-methionine + 4-hydroxy-N-methyltryptamine_4-phosphate <=> S-adenosyl-L-homocysteine + psilocybin + H+
|
2.1.1.345
psilocybin synthase
|
–
|
| |
BRENDA:
BR52248
KEGG:
R11936
MetaCyc:
RXN-19092
|
|
|
|
S-adenosyl-L-methionine + 4-hydroxytryptamine_4-phosphate <=> S-adenosyl-L-homocysteine + 4-hydroxy-N-methyltryptamine_4-phosphate + H+
|
2.1.1.345
psilocybin synthase
|
–
|
| |
BRENDA:
BR52247
KEGG:
R11935
MetaCyc:
RXN-19091
|
|
|
|
tryptamine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 4-hydroxytryptamine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.99.59
tryptamine 4-monooxygenase
|
–
|
| |
MetaCyc:
RXN-19089
|
|
