|
|
beta-methylmalyl-CoA <=> 2-methylfumaryl-CoA + H2O
|
4.2.1.148
2-methylfumaryl-CoA hydratase
4.2.1.153
3-methylfumaryl-CoA hydratase
|
–
–
|
| |
BRENDA:
BR51001
KEGG:
R05076
MetaCyc:
RXN-8960
|
|
|
|
L-threo-3-methylaspartate <=> L-glutamate
|
5.4.99.1
methylaspartate mutase
|
–
|
| |
BRENDA:
BR33
KEGG:
R00262
MetaCyc:
METHYLASPARTATE-MUTASE-RXN
SABIO-RK:
767
|
|
|
|
acetyl-CoA + H2O + oxaloacetate <=> citrate + CoA + H+
|
2.3.3.1
citrate (Si)-synthase
2.3.3.14
homocitrate synthase
2.3.3.16
citrate synthase (unknown stereospecificity)
2.3.3.3
citrate (Re)-synthase
|
–
–
–
–
|
| |
BRENDA:
BR44118
KEGG:
R00351
MetaCyc:
CITSYN-RXN;
RXN-14905
SABIO-RK:
267
|
|
|
|
NAD+ + H2O + L-glutamate <=> NADH + 2-oxoglutarate + NH3 + H+
|
1.4.1.14
glutamate synthase (NADH)
1.4.1.2
glutamate dehydrogenase
1.4.1.3
glutamate dehydrogenase [NAD(P)+]
1.4.1.4
glutamate dehydrogenase (NADP+)
1.4.1.5
L-amino-acid dehydrogenase
|
–
–
–
–
–
|
| |
BRENDA:
BR36868
KEGG:
R00243
MetaCyc:
GLUTAMATE-DEHYDROGENASE-NADP+-RXN_WOP;
GLUTAMATE-DEHYDROGENASE-RXN
SABIO-RK:
755
|
|
|
|
cis-aconitate + H2O <=> isocitrate
|
4.2.1.3
aconitate hydratase
|
–
|
| |
BRENDA:
BS18708
KEGG:
R01900
MetaCyc:
ACONITATEHYDR-RXN
SABIO-RK:
273
|
|
|
|
electron-transfer_quinone + succinate <=> electron-transfer_quinol + fumarate
|
1.3.5.1
succinate dehydrogenase
|
–
|
| |
MetaCyc:
RXN-14971
|
|
|
|
(R)-2-methylmalonyl-CoA <=> succinyl-CoA
|
5.4.99.2
methylmalonyl-CoA mutase
5.4.99.63
ethylmalonyl-CoA mutase
5.4.99.64
2-hydroxyisobutanoyl-CoA mutase
|
–
–
–
|
| |
BRENDA:
BR249;
BS380077;
BS390473
KEGG:
R00833
MetaCyc:
METHYLMALONYL-COA-MUT-RXN
SABIO-RK:
10453;
1174
|
|
|
|
(3S)-3-carboxy-3-hydroxypropanoyl-CoA <=> glyoxylate + acetyl-CoA
|
4.1.3.24
malyl-CoA lyase
|
–
|
| |
BRENDA:
BR3371;
BS444081
KEGG:
R00473
MetaCyc:
MALYL-COA-LYASE-RXN
|
|
|
|
succinyl-CoA + mesaconate <=> 2-methylfumaryl-CoA + succinate
|
2.8.3.26
succinyl-CoA:mesaconate CoA transferase
|
–
|
| |
BRENDA:
BR52650
KEGG:
R10904
MetaCyc:
RXN-12168
|
|
|
|
(S)-malate <=> fumarate + H2O
|
4.2.1.2
fumarate hydratase
4.2.1.34
(S)-2-methylmalate dehydratase
|
–
–
|
| |
BRENDA:
BR3389
KEGG:
R01082
MetaCyc:
FUMHYDR-RXN
SABIO-RK:
256
|
|
|
|
succinate + CoA + ATP <=> succinyl-CoA + ADP + phosphate
|
6.2.1.13
acetate---CoA ligase (ADP-forming)
6.2.1.4
succinate---CoA ligase (GDP-forming)
6.2.1.5
succinate---CoA ligase (ADP-forming)
|
–
–
–
|
| |
BRENDA:
BR88
KEGG:
R00405
MetaCyc:
SUCCCOASYN-RXN
SABIO-RK:
260
|
|
|
|
(S)-malate + NAD+ <=> oxaloacetate + NADH + H+
|
1.1.1.28
D-lactate dehydrogenase
1.1.1.299
malate dehydrogenase [NAD(P)+]
1.1.1.337
L-2-hydroxycarboxylate dehydrogenase (NAD+)
1.1.1.37
malate dehydrogenase
1.1.1.375
L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
1.1.1.38
malate dehydrogenase (oxaloacetate-decarboxylating)
1.1.1.81
hydroxypyruvate reductase
1.1.1.82
malate dehydrogenase (NADP+)
1.1.1.85
3-isopropylmalate dehydrogenase
1.1.1.95
phosphoglycerate dehydrogenase
1.1.1.96
diiodophenylpyruvate reductase
|
–
–
–
–
–
–
–
–
–
–
–
|
| |
BRENDA:
BR29300;
BS188027
KEGG:
R00342
MetaCyc:
MALATE-DEH-RXN;
RXN-10813_WOP
|
|
|
|
L-threo-3-methylaspartate <=> NH3 + mesaconate
|
4.3.1.2
methylaspartate ammonia-lyase
|
–
|
| |
BRENDA:
BR487
KEGG:
R03696
MetaCyc:
METHYLASPARTATE-AMMONIA-LYASE-RXN
|
|
|
|
(3S)-3-carboxy-3-hydroxypropanoyl-CoA + H2O <=> (S)-malate + CoA + H+
|
3.1.2.30
(3S)-malyl-CoA thioesterase
|
–
|
| |
BRENDA:
BR50984
KEGG:
R10612
MetaCyc:
RXN-14937
|
|
|
|
(R)-2-methylmalonyl-CoA <=> (S)-methylmalonyl-CoA
|
5.1.99.1
methylmalonyl-CoA epimerase
|
–
|
| |
BRENDA:
BR204;
BS970
KEGG:
R02765
MetaCyc:
METHYLMALONYL-COA-EPIM-RXN
SABIO-RK:
2642
|
|
|
|
isocitrate + NADP+ <=> 2-oxoglutarate + CO2 + NADPH
|
1.1.1.286
isocitrate---homoisocitrate dehydrogenase
1.1.1.41
isocitrate dehydrogenase (NAD+)
1.1.1.42
isocitrate dehydrogenase (NADP+)
|
–
–
–
|
| |
BRENDA:
BR29305;
BS370920
KEGG:
R00267
MetaCyc:
ISOCITDEH-RXN
SABIO-RK:
14842;
15247;
269
|
|
|
|
ATP + propionyl-CoA + HCO3- <=> H+ + (S)-methylmalonyl-CoA + phosphate + ADP
|
6.4.1.2
acetyl-CoA carboxylase
6.4.1.3
propionyl-CoA carboxylase
|
–
–
|
| |
BRENDA:
BR155
KEGG:
R01859
MetaCyc:
PROPIONYL-COA-CARBOXY-RXN
SABIO-RK:
1929
|
|
|
|
beta-methylmalyl-CoA <=> glyoxylate + propionyl-CoA
|
4.1.3.24
malyl-CoA lyase
|
–
|
| |
BRENDA:
BR50832
KEGG:
R00934
MetaCyc:
RXN-8961
|
|
|
|
citrate <=> cis-aconitate + H2O
|
4.2.1.117
2-methylcitrate dehydratase (2-methyl-trans-aconitate forming)
4.2.1.3
aconitate hydratase
|
–
–
|
| |
BRENDA:
BR419
KEGG:
R01325
MetaCyc:
ACONITATEDEHYDR-RXN
SABIO-RK:
268
|
|
