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isopropanol biosynthesis (engineered)

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
acetoacetate + H+ <=> acetone + CO2 2-oxopropyl-CoM reductase (carboxylating) acetoacetate decarboxylase

2-propanol + NADP+ <=> acetone + NADPH + H+ alcohol dehydrogenase glycerol 2-dehydrogenase (NADP+) carbonyl reductase (NADPH) alcohol dehydrogenase (NADP+) (R,R)-butanediol dehydrogenase alcohol dehydrogenase [NAD(P)+] isopropanol dehydrogenase (NADP+)

pyruvate + CoA + oxidized_ferredoxin <=> acetyl-CoA + CO2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ pyruvate synthase 2-oxoacid oxidoreductase (ferredoxin) 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)

acetyl-CoA <=> acetoacetyl-CoA + CoA hydroxymethylglutaryl-CoA reductase (NADPH) acetyl-CoA C-myristoyltransferase acetyl-CoA C-acyltransferase [acyl-carrier-protein] S-acetyltransferase acetyl-CoA C-acetyltransferase

H2O + acetoacetyl-CoA <=> H+ + acetoacetate + CoA acetyl-CoA hydrolase acetoacetyl-CoA hydrolase ADP-dependent short-chain-acyl-CoA hydrolase 2-aminobenzoylacetyl-CoA thioesterase

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