|
|
propionyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> 6-Deoxyerythronolide_b + CoA + CO2 + H2O + NADP+
|
2.3.1.94
6-deoxyerythronolide-B synthase
|
–
|
| |
BRENDA:
BR44097
KEGG:
R00918
MetaCyc:
ERYTHRONOLIDE-SYNTHASE-RXN
|
|
|
|
6-Deoxyerythronolide_b + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> erythronolide_B + H2O + oxidized_ferredoxin
|
1.14.15.35
6-deoxyerythronolide B hydroxylase
|
–
|
| |
BRENDA:
BR50927
KEGG:
R05270
MetaCyc:
RXN-12918
|
|
|
|
dTDP-beta-L-mycarose + erythronolide_B <=> 3-alpha-mycarosylerythronolide_B + dTDP + H+
|
2.4.1.328
erythronolide mycarosyltransferase
|
–
|
| |
BRENDA:
BR50870
KEGG:
R05530
MetaCyc:
RXN-12933
|
|
|
|
TDP-3-dimethylamino-4,6-dideoxy-alpha-D-glucopyranose + 3-alpha-mycarosylerythronolide_B <=> erythromycin_D + dTDP + H+
|
2.4.1.278
3-alpha-mycarosylerythronolide B desosaminyl transferase
|
–
|
| |
BRENDA:
BR49893
KEGG:
R05531
MetaCyc:
RXN-12808
|
|
