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ergotamine biosynthesis
| State Icon | Reaction | EC-Number | Confidence maximal confidence score from EnzymeDetector | |
|---|---|---|---|---|
| paspalic_acid <=> lysergate |
5.3.3
|
–
|
||
| agroclavine + NADP+ <=> 6,8-dimethyl-6,7,8,9-tetradehydroergoline + NADPH + H+ |
1.5.1.46
agroclavine dehydrogenase
|
–
|
||
| elymoclavine_aldehyde + O2 + NADPH <=> paspalic_acid + H2O + NADP+ |
1.14.13
|
–
|
||
| chanoclavine-I_aldehyde <=> 6,8-dimethyl-6,7,8,9-tetradehydroergoline + H2O |
not assigned |
–
|
||
| elymoclavine + O2 + NADPH + H+ <=> elymoclavine_aldehyde + H2O + NADP+ |
1.14.13
|
–
|
||
| agroclavine + O2 + NADPH + H+ <=> elymoclavine + NADP+ + H2O |
1.14.13
|
–
|
||
| lysergate + L-alanine + L-phenylalanine + L-proline + H+ + acceptor <=> ergotamine + H2O + reduced_acceptor |
not assigned |
–
|
||