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androgen biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
testosterone + NADP+ <=> 4-androstene-3,17-dione + NADPH + H+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
1.1.1.148 estradiol 17alpha-dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)











pregnenolone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 17alpha-hydroxypregnenolone + oxidized_[NADPH-hemoprotein_reductase] + H2O 1.14.14.19 steroid 17alpha-monooxygenase

5alpha-dihydrotestosterone + NADP+ <=> testosterone + H+ + NADPH 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
1.3.99.5 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor)


17alpha-hydroxypregnenolone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> dehydroepiandrosterone + acetate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+ 1.14.14.32 17alpha-hydroxyprogesterone deacetylase

5-androstene-3,17-dione <=> 4-androstene-3,17-dione 2.5.1.18 glutathione transferase
5.3.3.1 steroid Delta-isomerase


dehydroepiandrosterone + NAD+ <=> 5-androstene-3,17-dione + NADH + H+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase


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