|
|
testosterone + NADP+ <=> 4-androstene-3,17-dione + NADPH + H+
|
1.1.1.146
11beta-hydroxysteroid dehydrogenase
1.1.1.148
estradiol 17alpha-dehydrogenase
1.1.1.184
carbonyl reductase (NADPH)
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.209
3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213
3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.239
3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.50
3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.51
3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62
17beta-estradiol 17-dehydrogenase
1.1.1.64
testosterone 17beta-dehydrogenase (NADP+)
|
–
–
–
–
–
–
–
–
–
–
–
|
| |
BRENDA:
BR29315;
BS438469
KEGG:
R01838
MetaCyc:
1.1.1.51-RXN;
1.1.1.64-RXN
SABIO-RK:
1917
|
|
|
|
pregnenolone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 17alpha-hydroxypregnenolone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.19
steroid 17alpha-monooxygenase
|
–
|
| |
MetaCyc:
RXN66-340
|
|
|
|
5alpha-dihydrotestosterone + NADP+ <=> testosterone + H+ + NADPH
|
1.3.1.22
3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
1.3.99.5
3-oxo-5alpha-steroid 4-dehydrogenase (acceptor)
|
–
–
|
| |
BRENDA:
BS258429
KEGG:
R02497
MetaCyc:
RXN66-343
SABIO-RK:
11551
|
|
|
|
17alpha-hydroxypregnenolone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> dehydroepiandrosterone + acetate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.32
17alpha-hydroxyprogesterone deacetylase
|
–
|
| |
MetaCyc:
RXN66-341
|
|
|
|
5-androstene-3,17-dione <=> 4-androstene-3,17-dione
|
2.5.1.18
glutathione transferase
5.3.3.1
steroid Delta-isomerase
|
–
–
|
| |
BRENDA:
BS1076
KEGG:
R09955
MetaCyc:
RXN66-362
SABIO-RK:
7930
|
|
|
|
dehydroepiandrosterone + NAD+ <=> 5-androstene-3,17-dione + NADH + H+
|
1.1.1.145
3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.51
3(or 17)beta-hydroxysteroid dehydrogenase
|
–
–
|
| |
BRENDA:
BS257032
KEGG:
R09957
MetaCyc:
RXN66-342
SABIO-RK:
7900
|
|
