Copied!

Pathway Search



UMP biosynthesis II

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
orotidine_5''-phosphate + diphosphate <=> 5-phospho-alpha-D-ribose_1-diphosphate + Orotate 2.4.2.10 orotate phosphoribosyltransferase

L-glutamine + H2O <=> L-glutamate + NH3 1.4.1.13 glutamate synthase (NADPH)
1.4.1.14 glutamate synthase (NADH)
1.4.7.1 glutamate synthase (ferredoxin)
2.3.2.2 gamma-glutamyltransferase
2.4.2
2.4.2.14 amidophosphoribosyltransferase
3.4.11.17 tryptophanyl aminopeptidase
3.5.1.1 asparaginase
3.5.1.2 glutaminase
3.5.1.38 glutamin-(asparagin-)ase
3.5.1.43 peptidyl-glutaminase
3.5.1.44 protein-glutamine glutaminase
4.3.1.B2
4.3.2.10 imidazole glycerol-phosphate synthase
4.3.3.6 pyridoxal 5'-phosphate synthase (glutamine hydrolysing)
6.3.4.2 CTP synthase (glutamine hydrolysing)
6.3.5.13 lipid II isoglutaminyl synthase (glutamine-hydrolysing)
6.3.5.2 GMP synthase (glutamine-hydrolysing)
6.3.5.4 asparagine synthase (glutamine-hydrolysing)
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)
6.3.5.6 asparaginyl-tRNA synthase (glutamine-hydrolysing)
6.3.5.7 glutaminyl-tRNA synthase (glutamine-hydrolysing)






















L-dihydroorotate + H2O <=> H+ + L-carbamoyl-L-aspartate 3.5.2.3 dihydroorotase

L-dihydroorotate + fumarate <=> Orotate + succinate 1.3.98.1 dihydroorotate dehydrogenase (fumarate)

L-aspartate + Carbamoyl_phosphate <=> H+ + L-carbamoyl-L-aspartate + phosphate 2.1.3.2 aspartate carbamoyltransferase

ATP + HCO3- + NH3 <=> ADP + phosphate + Carbamoyl_phosphate + H+ 6.3.4.16 carbamoyl-phosphate synthase (ammonia)
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)


H+ + orotidine_5''-phosphate <=> CO2 + UMP 4.1.1.23 orotidine-5'-phosphate decarboxylase

Visualization of the pathway