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Nitrogen metabolism

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
Carbamate + ATP <=> Carbamoyl_phosphate + ADP 2.7.2.2 carbamate kinase
6.3.4.14 biotin carboxylase
6.3.4.16 carbamoyl-phosphate synthase (ammonia)
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)




NADP+ + H2O + L-glutamate <=> NADPH + 2-oxoglutarate + NH3 + H+ 1.4.1.13 glutamate synthase (NADPH)
1.4.1.2 glutamate dehydrogenase
1.4.1.3 glutamate dehydrogenase [NAD(P)+]
1.4.1.4 glutamate dehydrogenase (NADP+)




L-glutamate + oxidized_ferredoxin <=> 2-oxoglutarate + L-glutamine + reduced_ferredoxin_[iron-sulfur]_cluster + H+ 1.4.7.1 glutamate synthase (ferredoxin)

L-glutamate + NADP+ <=> H+ + L-glutamine + 2-oxoglutarate + NADPH 1.4.1.13 glutamate synthase (NADPH)
1.4.1.B5


NO + NH3 <=> N2O + H2O 1.7.1.14 nitric oxide reductase [NAD(P)+, nitrous oxide-forming]

NH3 + L-glutamate + ATP <=> H+ + L-glutamine + ADP + phosphate 6.3.1.2 glutamine synthetase

1-Nitropropane + H2O + O2 <=> an_aldehyde + nitrite + H2O2 1.7.3.1 nitroalkane oxidase

NH3 + H2O + NAD+ <=> H+ + hydroxylamine + NADH 1.7.1.10 hydroxylamine reductase (NADH)
1.7.1.4 nitrite reductase [NAD(P)H]
1.7.99.1 hydroxylamine reductase



nitrate + reduced_acceptor <=> nitrite + acceptor 1.5.1.20 methylenetetrahydrofolate reductase [NAD(P)H]
1.7.7.2 ferredoxin---nitrate reductase
1.7.99
1.9.6.1 nitrate reductase (cytochrome)




2 Ferrocytochrome + 2 H+ + nitrate <=> 2 Ferrocytochrome + nitrite + H2O 1.9.6.1 nitrate reductase (cytochrome)

NO + H2O + ferricytochrome_c <=> nitrite + ferricytochrome_c + 2 H+ 1.7.2.1 nitrite reductase (NO-forming)
1.7.2.6 hydroxylamine dehydrogenase


HCO3- <=> H2O + CO2 1.6.5.4 monodehydroascorbate reductase (NADH)
4.2.1.1 carbonic anhydrase


N2O + NADP+ + H2O <=> NO + NADPH + H+ 1.7.1.14 nitric oxide reductase [NAD(P)+, nitrous oxide-forming]
1.7.2.5 nitric oxide reductase (cytochrome c)


reduced_flavodoxin + N2 + ATP + H2O <=> flavin + NH3 + H2 + ADP + phosphate + H+ 1.19.6.1 nitrogenase (flavodoxin)

NAD+ + H2O + L-glutamate <=> NADH + 2-oxoglutarate + NH3 + H+ 1.4.1.14 glutamate synthase (NADH)
1.4.1.2 glutamate dehydrogenase
1.4.1.3 glutamate dehydrogenase [NAD(P)+]
1.4.1.4 glutamate dehydrogenase (NADP+)
1.4.1.5 L-amino-acid dehydrogenase





L-glutamate + NAD+ <=> L-glutamine + 2-oxoglutarate + NADH + H+ 1.4.1.13 glutamate synthase (NADPH)
1.4.1.14 glutamate synthase (NADH)


1-Nitropropane + H2O + O2 <=> acetone + nitrite + H2O2 1.7.3.1 nitroalkane oxidase

nitrite + H2O + NAD+ <=> H+ + nitrate + NADH 1.17.3.2 xanthine oxidase
1.7.1.1 nitrate reductase (NADH)
1.7.1.2 nitrate reductase [NAD(P)H]
1.7.1.3 nitrate reductase (NADPH)




R-CN + H2O <=> a_carboxylate + NH3 3.5.5.1 nitrilase
3.5.5.2 ricinine nitrilase
3.5.5.5 arylacetonitrilase
3.5.5.7 aliphatic nitrilase




NH3 + H2O + NAD+ <=> nitrite + NADH + H+ 1.7.1.10 hydroxylamine reductase (NADH)
1.7.1.15 nitrite reductase (NADH)
1.7.1.4 nitrite reductase [NAD(P)H]



reduced_ferredoxin_[iron-sulfur]_cluster + N2 + ATP + H2O <=> oxidized_ferredoxin + H2 + NH3 + ADP + phosphate + H+ 1.18.6.1 nitrogenase
1.18.6.2 vanadium-dependent nitrogenase
1.19.6.1 nitrogenase (flavodoxin)



NH3 + H2O + oxidized_ferredoxin <=> nitrite + reduced_ferredoxin_[iron-sulfur]_cluster + H+ 1.7.7.1 ferredoxin---nitrite reductase
1.8.7.1 assimilatory sulfite reductase (ferredoxin)


NO + azide <=> N2O + N2 1.7.1.14 nitric oxide reductase [NAD(P)+, nitrous oxide-forming]

N2O + 2 ferricytochrome_c + H2O <=> 2 NO + 2 ferricytochrome_c + 2 H+ 1.7.2.5 nitric oxide reductase (cytochrome c)

nitrite + azurin <=> NO + oxidized_azurin 1.7.2.1 nitrite reductase (NO-forming)

N2O + NAD+ + H2O <=> NO + NADH + H+ 1.7.1.14 nitric oxide reductase [NAD(P)+, nitrous oxide-forming]
1.7.2.5 nitric oxide reductase (cytochrome c)


nitrite + H2O + NADP+ <=> H+ + nitrate + NADPH 1.7.1.1 nitrate reductase (NADH)
1.7.1.2 nitrate reductase [NAD(P)H]
1.7.1.3 nitrate reductase (NADPH)



hydrazine + H2O + 3 ferricytochrome_c <=> NO + NH3 + 3 ferricytochrome_c 1.7.2.7 hydrazine synthase

NH3 + NADP+ + H2O <=> nitrite + NADPH + H+ 1.7.1.4 nitrite reductase [NAD(P)H]
1.7.7.1 ferredoxin---nitrite reductase
1.8.1.2 assimilatory sulfite reductase (NADPH)



N2 + H2O + 2 ferricytochrome_c <=> N2O + 2 ferricytochrome_c + 2 H+ 1.7.2.4 nitrous-oxide reductase

Formamide + H2O <=> formate + NH3 3.5.1.49 formamidase
3.5.1.56 N,N-dimethylformamidase


reduced_ferredoxin_[iron-sulfur]_cluster + N2 + ATP + H2O <=> oxidized_ferredoxin + H2 + NH3 + ADP + phosphate + H+ 1.18.6.1 nitrogenase
1.18.6.2 vanadium-dependent nitrogenase
1.19.6.1 nitrogenase (flavodoxin)



nitrite + oxidized_ferredoxin + H2O <=> nitrate + reduced_ferredoxin_[iron-sulfur]_cluster + H+ 1.7.7.2 ferredoxin---nitrate reductase

NH3 + 2 H2O + 6 ferricytochrome_c <=> nitrite + 6 ferricytochrome_c + 7 H+ 1.7.2.2 nitrite reductase (cytochrome; ammonia-forming)

Cyanate + HCO3- + H+ <=> Carbamate + CO2 4.2.1.104 cyanase

hydroxylamine + H2O + 4 ferricytochrome_c <=> nitrite + 4 ferricytochrome_c + 5 H+ 1.7.2.2 nitrite reductase (cytochrome; ammonia-forming)
1.7.2.6 hydroxylamine dehydrogenase
1.7.99.1 hydroxylamine reductase



nitrate + a_quinol <=> nitrite + a_quinone + H2O 1.7.5.1 nitrate reductase (quinone)

Carbamate + H+ <=> CO2 + NH3 3.5.1.110 ureidoacrylate amidohydrolase
4.2.1.104 cyanase


ATP + NH3 + CO2 + H2O <=> ADP + phosphate + Carbamoyl_phosphate 6.3.4.16 carbamoyl-phosphate synthase (ammonia)
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)


nitroethane + O2 + FMNH2 <=> acetaldehyde + nitrite + H2O + FMN + H+ 1.13.12.16 nitronate monooxygenase
1.7.3.1 nitroalkane oxidase


hydrazine + 4 ferricytochrome_c <=> N2 + 4 ferricytochrome_c 1.7.2.8 hydrazine dehydrogenase

NH3 + O2 + ubiquinol <=> hydroxylamine + H2O + ubiquinone 1.14.99.39 ammonia monooxygenase

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