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L-homomethionine biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
L-methionine + a_2-oxo_carboxylate <=> 4-methylsulfanyl-2-oxobutanoate + proteinogenic_amino_acid 2.6.1.88 methionine transaminase

5-methylthio-2-oxopentanoate + proteinogenic_amino_acid <=> L-homomethionine + a_2-oxo_carboxylate 2.6.1

2-[(2''-methylsulfanyl)ethyl]malate <=> 2-[(2''-methylsulfanyl)ethyl]maleate + H2O 4.2.1.170 2-(omega-methylthio)alkylmalate dehydratase

2-[(2''-methylsulfanyl)ethyl]maleate + H2O <=> 3-[(2''-methylsulfanyl)ethyl]malate not assigned

2-[2-(methylsulfanyl)ethyl]-3-oxobutanedioate + H+ <=> 5-methylthio-2-oxopentanoate + CO2 not assigned

4-methylsulfanyl-2-oxobutanoate + acetyl-CoA + H2O <=> 2-[(2''-methylsulfanyl)ethyl]malate + CoA + H+ 2.3.3.17 methylthioalkylmalate synthase

3-[(2''-methylsulfanyl)ethyl]malate + NAD+ <=> 2-[2-(methylsulfanyl)ethyl]-3-oxobutanedioate + NADH + H+ 1.1.1

Visualization of the pathway