Pathway Search

C20 prostanoid biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
prostaglandin_H2 <=> thromboxane_A2 thromboxane-A synthase

thioredoxin + prostaglandin_H2 <=> thioredoxin_disulfide + prostaglandin_F2alpha prostamide/prostaglandin F2alpha synthase

prostaglandin_H2 <=> Prostaglandin_D2 prostaglandin-D synthase prostaglandin-E synthase prostaglandin-I synthase

prostaglandin_H2 <=> prostaglandin_I2 prostaglandin-I synthase

arachidonic_acid + O2 + reduced_acceptor <=> prostaglandin_H2 + H2O + acceptor prostaglandin-endoperoxide synthase

prostaglandin_E2 + NAD+ <=> 15-ketoprostaglandin_E2 + NADH + H+ 15-hydroxyprostaglandin dehydrogenase (NAD+) prostaglandin-E2 9-reductase

prostaglandin_H2 <=> prostaglandin_E2 prostaglandin-E synthase

Visualization of the pathway