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C20 prostanoid biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
prostaglandin_H2 <=> thromboxane_A2 5.3.99.5 thromboxane-A synthase

thioredoxin + prostaglandin_H2 <=> thioredoxin_disulfide + prostaglandin_F2alpha 1.11.1.20 prostamide/prostaglandin F2alpha synthase

prostaglandin_H2 <=> Prostaglandin_D2 5.3.99.2 prostaglandin-D synthase
5.3.99.3 prostaglandin-E synthase
5.3.99.4 prostaglandin-I synthase



prostaglandin_H2 <=> prostaglandin_I2 5.3.99.4 prostaglandin-I synthase

arachidonic_acid + O2 + reduced_acceptor <=> prostaglandin_H2 + H2O + acceptor 1.14.99.1 prostaglandin-endoperoxide synthase

prostaglandin_E2 + NAD+ <=> 15-ketoprostaglandin_E2 + NADH + H+ 1.1.1.141 15-hydroxyprostaglandin dehydrogenase (NAD+)
1.1.1.189 prostaglandin-E2 9-reductase


prostaglandin_H2 <=> prostaglandin_E2 5.3.99.3 prostaglandin-E synthase

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