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4-hydroxy-2-nonenal detoxification

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
4-hydroxy-2-nonenal-[L-Cys]_conjugate + acetyl-CoA <=> 4-hydroxy-2-nonenal-N-acetyl-L-cysteine + CoA + H+ 2.3.1.80 cysteine-S-conjugate N-acetyltransferase

glutathione + 4-hydroxy-2-nonenal <=> S-(4-hydroxy-1-oxononan-3-yl)glutathione 2.5.1.18 glutathione transferase

S-(4-hydroxy-1-oxononan-3-yl)glutathione + H2O <=> 4-hydroxy-2-nonenal-[Cys-Gly]_conjugate + L-glutamate 3.4.19.13 glutathione gamma-glutamate hydrolase
3.4.19.9 folate gamma-glutamyl hydrolase


4-hydroxy-2-nonenal-[Cys-Gly]_conjugate + H2O <=> 4-hydroxy-2-nonenal-[L-Cys]_conjugate + glycine 3.4.11.2 membrane alanyl aminopeptidase
3.4.13.23 cysteinylglycine-S-conjugate dipeptidase


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